351. Adulteration of epinephrine chloride solution.    U. S. v. 12 Bottles of Epine
phrine Chloride Solution.   Default decree of condemnation and destruc-
tion.     (F. D. C. No. 2408.    Sample Nos. 15179-E, 15266-E.)
This product had been shipped in interstate commerce and was in interstate
commerce at the time of examination, at which time it was found that it did
not conform to the requirements of the United States Pharmacopoeia.
On July 23, 1940, the United States attorney for the Southern District of Iowa
filed a libel against 12 bottles of epinephrine chloride solution at Des Moines,
Iowa, alleging that the article had been shipped in interstate commerce on or
about January 18,1937, by the Difco Laboratories, Inc., from Detroit, Mich.; and
charging that it was adulterated.
It was alleged to be adulterated in that it purported to be and was represented
as a drug the name of which is recognized in the United States Pharmacopoeia,
but its quality fell below the standard set forth in the pharmacopoeia since
examination showed that it was dark brown in color and contained sediment;
whereas epinephrine chloride solution is a synonym for a solution of epinephrine
hydrochloride, a designation used by the United States Pharmacopoeia, which
states that a solution of epinephrine hydrochloride is "a nearly colorless * * *
liquid, gradually turning dark on exposure to air and light, and when the solution
has become brown in color, or contains a precipitate, it must be rejected."
On October 9, 1940, no claimant having appeared, judgment of condemnation
was entered and the product was ordered destroyed.