3511. Adulteration and misbranding of Cogenat tablets (conjugated estrogens).
U. S. v. 195 Bottles, etc.    (F. D. C. No. 31231.   Sample Nos. 1831-L,
1832-L.)
LIBEL FILED :   On or about July 5, 1951, Northern District of Georgia.
ALLEGED SHIPMENT:    On or about June 30 and July 8 and 19, 1949, by the
National Drug Co., from Philadelphia, Pa.
PRODUCT: Cogenat tablets (conjugated estrogens). 195 100-tablet bottles, 1
1,000-tablet bottle, and 19   100-tablet bottles at Atlanta, Ga.
Analysis showed that the 195-bottle lot contained a total amount of estrogenic
steroids calculated as not more than 0.38 mg. of sodium estrone sulfate per
tablet, and that the 1-bottle and the 19-bottle lots contained a total amount
sulfate per tablet.
ISABEL, IN PART : (195-bottle lot) "Cogenat 0.625. mg. Conjugated Estrogens"
and (1-bottle and 19-bottle lots) "Cogenat   1.25 mg.   Conjugated Estrogens."
NATURE or CHARGE: Adulteration, Section 501 (c), the strength of the article
in each of the two lots differed from that which it was represented to possess,
namely, 0.625 mg. and 1.25 mg., respectively, of conjugated estrogens expressed
as sodium estrone sulfate.
Misbranding, Section 502 (a), the label statements on the two lots of the
article, namely, "Each tablet contains: Conjugated Estrogens * * *
0.625 mg. [or "1.25 mg."] expressed as Sodium Estrone Sulfate" were false
and misleading as applied to an article containing less than the stated amounts
of estrogenic steroids calculated as sodium estrone sulfate.
DISPOSITION:   July 31, 1951.   Default decree of condemnation and destruction.