6550. Adulteration, of salol and auinine and adulteration and misbranding?
of Grip Pans capsules, capsules aspirin, mixed treatment capsules,?
sedative capsules, codeiphen capsules,- Migraine Preferred, No. 2,?
salol and acetphenetidin. TJ. S. * * * v. Joseph McManus (Phil??
adelphia Capsule Co.). Plea of nolo contendere. Fine, $150. (P. &?
D. No. 8705. I. S. Nos. 1560-m, 8813-m, 8815-m, 8816-m, 8818-m, 8819-m,?
8820-m,  8821-m.)
On June 13, 1918, the United States attorney for the Eastern District of?
Pennsylvania, acting upon a report by the Secretary of Agriculture, filed in?
the District Court of the United States for said district an information against?
Joseph McManus, trading as the Philadelphia Capsule Co., Philadelphia, Pa.,?
alleging shipment by said defendant on or about the dates indicated from the?
State of Pennsylvania into the State of New Jersey, of quantities of articles?
labeled in' part " Grip Pans Capsules," February 7, 1917, "Aspirin," " Mixed?
Treatment Capsules," " Sedative Capsules," May 9, 1917, " Codeiphen Cap??
sules," " Migraine, Pref. No. 2," and " Salol & Acetphenetidin," June 12, 1917,?
which were adulterated and misbranded, an<J on or about June 12, 1917, a?
quantity of an article labeled in part " Salol & Quinine," which was adulterated.
Analysesa of samples of the articles by the Bureau of Chemistry of this?
department showed the following results:
GRIP PANS.
Acetanilid   (per cent)?
28.15
(grains per ounce)?
about 123
Ammonium salicylate (calculated from salicylic acid)   (per??
cent)?
37. 38
Sodium bicarbonate (per cent)?
25.52
Plant tissue, moisture, etc.  (per cent)?
    8.95
ASPIRIN.
Average contents (10 capsules)   (grains)?
    3.585
Average shortage (10 capsules)   (grains)?
    1.415
(per cent)?
28. 3
Capsules are 28 per cent short of aspirin.
MIXED  TREATMENT  CAPSULES.
Iron as ferrous iodid (mg per capsule)?
15.7
Arsenic as arsenous iodid (mg per capsule)?
      . 32
Analysis shows not more than 3.72 minims sirup of ferrous?
iodid U.S.P. and 0.52 minims solution arsenous and mercuric?
iodids U.S.P. per capsule.
SEDATIVE CAPSULES.
172 capsules in bottle.
Ammonia as ammonium Bromid (grains per capsule)?
2. 25
Potassium bromid (grains)?
2.405
Sodium as sodium bromid (grains per capsule)?
2.143
CODEIPHEN CAPSULES.
Product contains 2.47 grains of acetanilid per capsule and no?
acetphenetidine and contained codein.
MIGRAINE, PREFERRED,  NO. 2.
186 capsules in bottle.?
Acetanilid (grains per capsule)?
2.51
56	
BUEEAU  OF  CHEMISTRY.	
[Supplement 61.
SALOL AND QUININE.
Salol (grains per capsule)?
1.61
(or 20 per cent less than the catalogue claim, which is 2 grains.)
SALOL AND ACETPHENETIDIN.
Acetphenetidin (grains per capsule)?
0.90
Salol (grains per capsule)?.?
1.80
The acetphenetidine is about 65 per cent less, and the salol is?
about 28 per cent less than the catalogue claim, which is 2.5 grs.?
of acetphenetidine and salol.
Adulteration of the article in each shipment was alleged in the information?
for the reason that its strength and purity fell below the professed standard?
under which it was sold.
Misbranding of Grip Pans was alleged for the reason that the statement,?
to wit, "Contains Acetanilide Derivative 125 grs. to oz. * * * Phenysal 1?,?
gr. Salipyrine 1 gr.", borne on the label attached to the bottle containing the?
article regarding it and the ingredients and substances contained therein, was?
false and misleading in that it represented that said capsules each contained?
125 grains of acetanilid derivative to the ounce, 1? grains phenysal, 1 grain?
salipyrin, whereas, in truth and in fact, said capsules contained no acetanilid?
derivative, phenysal, or salipyrin. Misbranding was alleged for the further?
reason that the 
article contained acetanilid, and the label failed to bear a?
statement of the quantity or proportion of the acetanilid contained therein.
Misbranding of the aspirin was alleged for the reason that the statement,?
to wit, "Aspirin 5 grains," borne on the label attached to the bottle containing?
the article, regarding it and the ingredients and substances contained therein,?
was false and misleading in that it represented that said capsules each con??
tained 5 grains of aspirin, whereas, in truth and in fact, they did not, but?
contained a less amount, to wit, 3.585 grains of aspirin.
Misbranding of the " Mixed Treatment Capsules " was alleged for the rea??
son that the statement, to wit, " Syrup Ferrous Iodide 5 min. * * * Solu??
tion Arsenous and Mercuric Iodides 2 min.," borne on the label attached to?
the bottle containing the article regarding it and the ingredients and substances?
contained therein, was false and misleading in that it represented that said?
capsules each contained 5 minims of sirup ferrous iodid and 2 minims of?
solution arsenous and mercuric iodids, whereas, in truth and in fact, said?
capsules did not contain 5 minims of sirup ferrous iodid and 2 minims of?
solution arsenous and mercuric iodids, but contained a less amount of sirup?
ferrous iodid and a less amount of solution arsenous and mercuric iodids.
Misbranding of the " Sedative Capsules" was alleged for the reason that?
the statements, to wit, " 200 capsules" and "Ammonium Bromide 2J gr.?
Sodium Bromide 2J gr. Potassium Bromide 2? gr.", borne on the label attached?
to the bottle containing the article regarding it and the ingredients and sub??
stances contained therein, were false and misleading in that they represented?
that said bottles contained 200 capsules and that said capsules each contained 2-??
grains ammonium bromid, 2? grains sodium bromid, and 1\ grains potassium?
bromid, whereas, in truth and in fact, said bottle did not contain 200 capsules,?
but contained a less amount, to wit, 172 capsules, and each of said capsules?
did not contain 2? grains ammonium bromid, 2? grains sodium bromid, and?
2? potassium bromid, but contained a less amount, to wit, ammonium bromid?
2.25 grains, sodium bromid 2.143 grains, and potassium bromid 2.405 grains.
N. J. 6501-6550.1 .SERVICE  AND REGULATORY ANNO-UNCEMENTS.	57
Misbranding of the " Codeiphen Capsules" was alleged for the reason that?
the statement, to wit, " Acetphenetidine 3 gr.", borne on the label attached to the?
bottle containing the article regarding it and the ingredients and substances?
contained therein, was false and misleading in that it represented that said?
capsules each contained 3 grains of acetphenetidin, whereas, in truth and in?
fact, said capsules contained no acetphenetidin; and for the further reason?
that it contained acetanilid, and the label failed to bear a statement of the?
quantity or proportion of acetanilid contained therein; and for the further?
reason that it contained codeine, a derivative of opium, and the label failed?
to bear a statement of the quantity or proportion of codeine, a derivative of?
opium, contained therein.
Misbranding of the " Migraine, Pref., No. 2 " was alleged for the reason that?
the statement, to wit, " 220," borne on the label attached to the bottle contain-"?
ing the article, regarding it, was false and misleading in that it represented that?
said bottle contained 200 capsules of the article, whereas, in truth and in fact,?
said bottle did not contain 200 capsules of the article, but did contain a less?
amount, to wit, 186 capsules of the article; and for the further reason that it?
contained acetanilid and the label failed to bear a statement of the quantity?
or proportion of acetanilid contained therein.
Misbranding of the " Salol and Acetphenetidin " was alleged for the reason?
that it contained acetphenetidin, a derivative of acetanilid, and the label?
failed to bear a statement of the quantity or proportion of acetphenetidin, a?
derivative of acetanilid, contained therein.
On December 12, 1918, the defendant entered a plea of nolo contendere to?
the information, and the court imposed a fine of $150.
O. F. MARVIN, Acting Secretary of Agriculture.
S. R. A.—Chem. Suppl. 62.