14955.?Adulteration  and  misbranding  of  quinine  sulphate  tablets,  nitro?
glycerin tablets, acetphenetidin tablets, morphine sulphate tablets,?
strychnine sulphate tablets, and belladonna tincture. U. S. v.?
Raymer   Pharmacal   Co.    Plea   of   nolo   contendere.     Fine,   $500.
(F. & D. No. 21559. I. S. Nos. 4952-x, 4954-x, 4955-x, 4956-x, 4969-x,?
6258-x, 6263-x, 7967-x, 7968-x, 7969-x.)
On January 4, 1927, the United States attorney for the Eastern District of?
Pennsylvania, acting upon a report by the Secretary of Agriculture, filed in the?
District Court of the United States for said district an information against the
N. J.. 14951-15000]     SERVICE   AND  REGULATORY  ANNOUNCEMENTS        503
Raymer Pharmacal Co., a corporation, trading at Philadelphia, Pa., alleging?
shipment,by said company, in violation of the food and drugs act, on or about?
December 29, 1925, from the State of Pennsylvania into the State of Maryland,?
of quantities of nitroglycerin tablets, acetphenetidin tablets, quinine sulphate?
tablets, and belladonna tincture, on or about January 2, February 19, and?
March 5, 1926, respectively, from the State of Pennsylvania into the State of?
New Jersey, of quantities of quinine sulphate tablets, nitroglycerin tablets,?
morphine sulphate tablets, and strychnine sulphate tablets, which said products?
were adulterated and misbranded. The articles were labeled in part, vari??
ously: "Tablets Quinine Sulphate * * * 1 gr.," "Nitroglycerin 1-100 Gr.,"?
"Nitroglycerin 1/200 gr.," "Tablets * * * Nitroglycerin * * * 1-50?
Grain," " Tablets Acetphenetidin 2 gr.," " Tablets Morphine Sulphate * * *?
? gr.," "Tablets Morphine Sulphate * * * ? Gr.," "Tablets Strychnine?
Sulphate 1-30 gr.," "Tincture * * * Belladonna * * * U. S. P.," as?
the case might be, "Raymer Pharmacal Co., Pharmaceutical Manufacturers?
Philadelphia."
Analysis by the Bureau of Chemistry of this department of samples of the?
articles showed that: The three samples of nitroglycerin tablets, labeled " 1/200?
gr.," " 1/100 Gr.," and " 1/50 Grain," respectively, contained 1/450 grain,?
1/230 grain, and 1/70 grain, respectively, of nitroglycerin per tablet; the?
sample of acetphenetidin tablets, labeled " 2 gr.," contained 1.74 grains of acet??
phenetidin per tablet; the two samples of quinine sulphate, labeled " 1 gr.,"?
contained ? grain of quinine sulphate per tablet; the two samples of morphine?
sulphate, labeled " ? gr." and " V8 Gr.," respectively, contained 2/9 grain and?
1/11 grain, respectively, of morphine sulphate per tablet; the sample of?
strychnine sulphate, labeled " 1/30 gr.," contained 1/35 grain of strychnine?
sulphate per tablet; the belladonna tincture yielded not less than 0.0382 gram?
of the total alkaloids of belladonna leaves per 100 mils.
Adulteration of the said tablets was alleged in substance in the information?
for the reason that their strength and purity fell below the professed standard?
and quality under which they were sold, in that the labels represented the said?
tablets to contain 1 grain of quinine sulphate, 1/100 grain of nitroglycerin,?
1/200 grain of nitroglycerin, 1/50 grain of nitroglycerin, 2 grains of acetphene??
tidin, ? grain of morphine sulphate, ? grain of morphine sulphate, or 1/30?
grain of strychnine sulphate, as the case might be, whereas each of said tablets?
contained less of the product than represented on the label thereof.
Adulteration of the belladonna tincture was alleged in the information for?
the reason that it was sold under and by a name recognized in the United?
States Pharmacopoeia and differed from the standard of strength, quality, and?
purity as determined by the test laid down in said pharmacopoeia, official at the?
time of investigation, in that it yielded not less than 0.0382 gram of the total?
alkaloids of belladonna leaves per 100 mils, whereas said pharmacopoeia pro??
vided that belladonna tincture, that is, tincture of belladonna leaves, should?
yield not more than 0.033 gram of the total alkaloids of belladonna leaves per?
100 mils, and the standard of strength, quality, and purity of the article was?
not declared on the container thereof.
Misbranding of the said tablets was alleged for the reason that the state??
ments, to wit, " Tablets Quinine Sulphate *? * * 1 gr.," " Nitroglycerin?
1-100 Gr.," "Nitroglycerin 1/200 gr.," "Tablets Nitroglycerin * * * 1-50?
Grain," " Tablets Acetphenetidin 2 gr.," " Tablets Morphine Sulphate * * *?
? gr.," "Tablets Morphine Sulphate * * * ? Gr.," "Tablets Strychnine?
Sulphate 1-30 gr.," as the case might be, borne on the labels of the respective?
products, were false and misleading, in that the said statements represented?
that each of said tablets contained the amount of the product declared on the?
label thereof, whereas the said tablets contained less than so declared.?
' Misbranding of the said belladonna tincture was alleged for the reason that?
the statement, to wit, "Tincture * * * Belladonna * * * U. S. P.,"?
borne on the label, was false and misleading, in that the said statement repre??
sented that the article was belladonna tincture which conformed to the tests?
laid down in the United States Pharmacopoeia, wThereas, in truth and in fact,?
it was not.
On March 18, 1927, a plea of nolo contendere to the information was entered?
on behalf of the defendant company, and the court imposed a fine of $500.
W. M. JABDINE, Secretary of Agriculture.
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BUEEAU   OP   CHEMISTRY	
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