18959. Misbranding of Gonolin.     U. S. v. 12 Packages of Gonolin.    Default 
decree of condemnation, forfeiture, and destruction.     (F. & D. No.
25171.    I. S. No. 7623.    S. No. 3416.)
Examination of a drug product, known as Gonolin, from the shipment herein 
described having shown that the carton label and an accompanying circular 
contained statements representing that the article possessed curative and 
therapeutic properties which, in fact, it did not possess, the Secretary of Agri- 
culture reported the matter to the United States attorney for the Northern 
District of Illinois.
On September 30, 1930, the United States attorney filed in the District Court 
of the United States for the district aforesaid a libel praying seizure and con- 
demnation of 12 packages of the said Gonolin at Chicago, Ill., alleging that the 
article had been shipped by the Lipoidal Laboratories, from New York, N. Y., 
April 25, 1930, and had been transported from the State of New York into the 
State of Illinois, and charging misbranding in violation of the food and drugs 
act as amended.
Analysis of a sample of the article by this department showed that it consisted 
essentially of a magnesium compound, phosphates, iodide, extracts of plant 
material, and water.
It was alleged in the libel that the article was misbranded in that the fol- 
lowing statements regarding the curative or therapeutic effects of the said 
article, appearing on the carton and in the accompanying circular, were false 
and fraudulent, and in that the said statements were applied to the article 
so as to represent falsely and fraudulently to purchasers and create in the 
minds of such purchasers the impression and belief that it was composed of or 
contained ingredients or medicinal agents or combinations, effective as a remedy 
for the diseases, ailments, and afflictions mentioned upon the said carton and 
in the said circular: (Carton) "Gonolin Proto-Enzyme Treatment for Gonor- 
rhea. * * * The length of treatment will vary with the general health of 
patient previous to the infection and in accordance with the virulence of the 
infection, some cases responding in from 10 to 12 injections, others requiring 24 
to 36 injections. During the early stages of treatment with Gonolin the dis- 
charge will probably be increased, but will gradually decrease and finally dis- 
appear entirely. * * * In chronic cases results depend upon duration of 
injection and involvement;" (circular) "In the treatment of Gonorrheal In- 
fection with Gonolin, the best result is obtained if the same or similar tech- 
nique is used as at the G. U. Clinic, Ward 35, Bellevue Hospital, New York 
City. We understand that at the G. U. Clinic in Bellevue Hospital, they com- 
mence the treatment of cases with 1 c. c. and if physiological reaction is not 
obtained through the use of this dose, the next injection consists of 2 c. c 
intramuscularly using a fine needle (1 inch, 24 gauge). In the majority of 
cases, the physiological reaction is reached by 2 c. c.; that means, the patient 
reports at the next Clinic Day, that a few hours after the administration of 
Gonolin, he felt a slight raise of temperature followed by a mild chill and 
also noticed a decided change in the discharge. In some cases, however, 3 to 
4 c. c. of Gonolin is necessary to obtain the physiological reaction. After this 
so important reaction is obtained, the case very rapidly improves physically 
as well as seriologically, as the charts of Ward 35, G. U. Clinic, Bellevue 
Hospital, prove the majority of patients clear up from 8 to 18 injections showing 
g. c. negative. Without obtaining the so important physiological reaction, the 
treatment will be unnecessarily prolonged to the dissatisfaction of the patient 
and the doctor, bringing unjust criticism upon Gonolin. * * * Some doctors, 
with vast experience in Gonolin therapy, prefer to start with massive doses (2 
c. c.) to obtain an immediate physiological reaction, thereby materially shorten- 
ing time of treatment."
On August 26, 1931, no claimant having appeared for the property, judgment 
of condemnation and forfeiture was entered, and it was ordered by the court 
thatthe product be destroyed by the United States marshal.
ABTHUB M. HYDE, Secretary of Agriculture.