20394. Adulteration and Misbranding of Vln: Iodine Comp., cinchopben 
tablets, Acetphenine tablets, quinine sulphate tablets, Bis-Ma-Cal 
tablets, Salacepben tablets, acetanilide compound tablets, salol 
capsules, sodium salicylate tablets, Kalmolax tablets, salol and 
phenacetin tablets, and grippe tablets. U.S. v. Llewellyn Labo- 
ratories, Inc. Plea of guilty. Fine, $150. (P. & D. no. 27570. I.S. 
nos. 26446, 29826, 29827, 29828, 29862, 29863, 29864, 29865, 29866, 29867, 
29869, 29872, 29873.)
This case involved a shipment of a liquid drug preparation known as Vin: 
Iodine Comp. and of various pharmaceuticals in tablet or capsule form. The 
Vin: Iodine Comp. was represented to contain phosphorus and bromine, 
whereas it contained no free bromine and no free phosphorus; it also con- 
tained less iodine than declared; and more alcohol than declared on the carton 
and circular. The tablets were found to contain a smaller amount of one or 
more of the essential drugs than labeled; the acetanilide compound tablets were 
not only deficient in acetanilid but contained citrated caffeine in excess of the 
declared amount. The labels of the Vin: Iodine Comp. and the grippe tablets 
also bore unwarranted therapeutic claims.
On August 3, 1932, the United States attorney for the Eastern District of 
Pennsylvania, acting upon a report by the Secretary of Agriculture, filed in 
the District Court of the United States for the district aforesaid an informa- 
tion against the Llewellyn Laboratories, Inc., a corporation, trading at Phila- 
delphia, Pa., alleging shipment by said company in violation of the Food and 
Drugs Act as amended, on November 19, 1930, and March 4, 1931, from the 
State of Pennsylvania into the State of Ohio, of a quantity of Vin: Iodine 
Comp.; and on or about March 4, March 18, March 30, and April 13, 1931, from 
the State of Pennsylvania into the State of New Jersey, of quantities of drug 
tablets, which said products were adulterated and misbranded. The Vin: 
Iodine Comp. was labeled in part: (Bottle) "Vin: Iodine Comp. Contains 35% 
Alcohol Phosphorus, Iodine and Bromine "; (carton) " Contains 15% Alcohol 
Phosphorus, Iodine and Bromide"; (circular) "Iodine gr. %, Bromine gr. %, 
Phosphorus gr. Vioo in each fluid-drachm." The tablets were labeled in part: 
" Cincophen 5 Grs."; "Acetphenine Acetphenetidin iy2 grs., Acetylsalicylic Acid 
3 grs. Caffeine y2 gr."; " Quinine Sulph. 2 gr."; " Bis-Ma-Cal Magnesium Curb. 
2 gr., Bismuth Submit. % gr., Calcium Curb. 3% gr."; " Salacephen * * * 
Acetphenetidin 2 grs."; "Acetanilide Comp. * * * Acetanilid 2 grs., Citrated 
Caffeine y2 gr."; " Salol 5 grs."; " Sodium Salicylate 5 Grs."; " Kalmolax Each 
tablet contains * * * *4 gr. Phenolphthalein"; " Salol and Phenacetine 
Salol in grs., Phenacetine 2% grs."; "Grippe Acetanilid 1% grs., Quinine 
Sulph. y2 gr." The articles were further labeled: "Llewellyn Laboratories, 
Inc. [or " Llewellyn Inc."] Philadelphia."
It was alleged in the information that the articles were adulterated in that 
their strength and purity fell below the professed standard and quality under 
which they were sold, in the following respects:
The Vin: Iodine Comp. was represented to contain phosphorus and bromine, 
it was represented to contain % grain of iodine, % grain of bromine, and 1/100 
grain of phosphorus in each fluiddrachm, whereas it contained not more than 
0.0414 (approximately 1/24 grain) of iodine per fluiddrachm, and contained no 
free bromine and no free phosphorus.
The cinchophen tablets were represented to contain in each 5 grains of 
cinchophen, whereas each tablet contained not more than 3.88 grains of 
cinchophen.
The Acetphenine tablets were represented to contain in each 3 grains of 
acetylsalicylic acid and % grain of caffeine, whereas the said tablets each 
contained less than 3 grains of acetylsalicylic acid, the two lots containing 
not more than 2.388 grains and 2.598 grains respectively, per tablet, and one 
lot contained less caffeine than represented, namely, not more than 0.413 grain 
of caffeine per tablet.
The quinine sulphate tablets were represented to contain in each 2 grains of 
quinine sulphate, whereas each tablet contained not more than 1.473 grains 
of quinine sulphate.
The Bis-Ma-Cal tablets were represented to contain in each 2 grains of 
magnesium carbonate, y2 grain of bismuth subnitrate, and 3% grains of calcium 
carbonate, whereas each of said tablets contained not more than 1.609 grains 
of magnesium carbonate, not more than 0.383 grain of bismuth subnitrate, 
and not more than 2.607 grains of calcium carbonate.
The Salacephen tablets were represented to contain in each 2 grains of 
acetphenetidin, whereas each of said tablets contained not more than 1.687 
grains of acetphenetidin.
The acetanilid compound tablets were represented to contain in each 2 
grains of acetanilid and y2 grain of citrated caffeine, whereas each of said 
tablets contained less acetanilid and more citrated caffeine, than represented, 
namely, not more than 1.605 grains of acetanilid and not less than 0.65 grain 
of citrated caffeine.
The salol capsules were represented to contain in each 5 grains of salol, 
whereas each capsule contained not more than 3.925 grains of salol.
The sodium salicylate tablets were represented to contain in each 5 grains 
of sodium salicylate, whereas each tablet contained not more than 3.939 grains 
of sodium salicylate.
The Kalmolax tablets were represented to contain in each % grain of 
phenolphthaleln, whereas each of said tablets contained not more than 0.221 
grain of phenolphthaleln.
The salol and phenacetin tablets were represented to contain in each 2% 
grains of salol and 2% grains of phenacetin, whereas each tablet contained 
not more than 2.137 grains of salol and not more than 2.144 grains of phenacetin.
The grippe tablets were represented to contain in each 1% grains of acetanilid 
and % grain of quinine sulphate, whereas each tablet contained not more than 
1.01 grains of acetanilid and not more than 0.432 grain of quinine sulphate.
Misbranding of the said Vin: Iodine Comp. was alleged for the reason that 
the statements, " Contains * * * Phosphorus * * * and Bromine" on 
the bottle label, the statement " Contains 15% Alcohol Phosphorus," borne on 
the carton, and the statements " Iodine gr. y6, Bromine gr. %, Phosphorus gr. 
1/100 in each fluiddrachm contains 15% Alcohol", appearing in the circular, 
were false and misleading, since the article contained more than 15 percent 
of alcohol, it contained less than y6 grain of iodine in each fluiddrachm and 
contained no free phosphorus and no free bromine. Misbranding of the Vin: 
Iodine Comp. was alleged for the further reason that the carton failed to bear 
a statement of the quantity or proportion of alcohol contained in the article, 
since the statement appearing on the carton was incorrect.
Misbranding of the remaining products was alleged for the reason that the 
statements (cinchophen tablets) " Cincophen 5 Grs.", (both lots of Acetphenine 
tablets) "Acetylsalicylic Acid 3 grs. * * * Tablet", (portion of said Acet- 
phenine tablets) "Caffeine y2 gr.", (quinine sulphate tablets) "Quinine Sulph. 
2 gr.", (Bis-Ma-Cal tablets) " Magnesium Curb. 2 gr. Bismuth Submit. y2 gr. 
Calcium Curb. 3% gr.", (salacephen tablets) "Acetphenetidin 2 grs.", (acetanilid 
compound tablets) "Acetanilide 2 grs. Citrated Caffeine y2 gr.", (salol tablets) 
M Salol 5 grs.", (sodium salicylate tablets) " Sodium Salicylate 5 grs.", (Wal- 
pole tablets) "Bach tablet contains   *    *    *    % gr. Phenolphthalein", (salol
and phenacetin tablets) " Salol 2% grs. Phenacetine 2% grs.", and (grippe tab- 
lets) "Acetanilid 1% grs. Quinine Sulph. % gr.", were false and misleading.
It was further alleged that the said Vin: Iodine Comp. was misbranded in 
that certain statements appearing in the circular shipped with the article falsely 
and fraudulently represented that it was effective as an active and satisfactory 
remedy for rickets in children and kindred conditions; and that the said grippe 
tablets were misbranded in that certain statements appearing on the bottle 
label falsely and fraudulently represented that the article was effective as a 
treatment, remedy, and cure for grippe.
On December 14, 1932, a plea of guilty to the information was entered on 
behalf of the defendant company, and the court imposed a fine of $150.
R. G. TuGWEtx, Acting Secretary of Agriculture.